| alr3731 | Genes and Mutants | | Genes and Mutants | posted by Cheng-Cai Zhang <cczhang at ibsm.cnrs-mrs.fr> at 2007-05-24 |
|---|
| GeneName | prpA | | ProductName | PrpA | | Function | A protein phosphatase (PP1, 2A, 2B-type), required for heterocyst development. | | Phenotype | yes | | PhenotypeDetails | Fails to grow under N2-fixing conditions; but grows normally with nitrate or ammonium. | | Comment | In the same gene cluster as pknE | | Medline | 9573144 |
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| alr0710 | Genes and Mutants | | Genes and Mutants | posted by Cheng-Cai Zhang <cczhang at ibsm.cnrs-mrs.fr> at 2007-05-22 |
|---|
| MutantName | deltapkn42 | | GeneName | pkn42 | | ProductName | Pkn42 | | Function | Together with Pkn41, belong to the HstK family of protein kinase family (with both a Ser/Thr kinase domain and a His kinase domain. Involed in iron homeostasis and nitrogen control | | PhenotypeDetails | Little phenotypes. When inactivated together with pkn41, grows poorly when both iron and combined-nitrogen source are limiting | | Medline | 16788191 |
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| all2096 | Genes and Mutants | | Genes and Mutants | posted by Allison Elizabeth McDonald <allison at utsc.utoronto.ca> at 2004-04-20 |
|---|
| GeneName | PTOX | | ProductName | plastoquinol terminal oxidase | | Function | PTOX is believed to oxidize plastoquinol to plastoquinone and toreduce oxygen to water. PTOX may represent the terminal oxidasein the process of chlororespiration. | | Comment | The assignment of this gene as PTOX is based on multiple sequencealignments and molecular phylogenies. The mRNA is expressed basedon RT-PCR and Northern analyses. | | Medline | 15082931 |
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| all4106 | Genes and Mutants | | Genes and Mutants | posted by Onassis Ancheta Aris <oaris at hawaii.edu> at 2003-11-26 |
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| GeneName | probable oxidoreductase |
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| alr3187 | Genes and Mutants | | Genes and Mutants | posted by Enrique Flores <eflores at ibvf.csic.es> at 2008-02-28 |
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| MutantName | CSS8 | | GeneName | bgtB | | ProductName | Periplasmic substrate-binding and transmembrane protein of the ABC-type transporter Bgt | | Function | Transport of basic amino acids | | Phenotype | yes | | PhenotypeDetails | Impaired amino acid transport | | DrugMarker | Nm/Km | | Comment | BgtB is a sort of fusion protein with periplasmic substrate-binding and transmembrane domains | | Medline | 18208492 |
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| all1284 | Genes and Mutants | | Genes and Mutants | posted by Enrique Flores <eflores at ibvf.csic.es> at 2008-02-28 |
|---|
| MutantName | CSR11 | | GeneName | natD | | ProductName | Transmembrane protein of the ABC-type transporter N-I | | Function | Transport of proline and hydrophobic amino acids | | Phenotype | yes | | PhenotypeDetails | Impaired amino acid transport and impaired diazotrophic growth | | DrugMarker | Sm/Sp | | AdditionalInformation | Medline ID: 18208492 | | Medline | 16135226 |
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| alr3732 | Genes and Mutants | | Genes and Mutants | posted by Cheng-Cai Zhang <cczhang at ibsm.cnrs-mrs.fr> at 2007-05-24 |
|---|
| GeneName | pknE | | ProductName | PknE | | Function | A putative Ser/Thr kinase, required for heterocyst development | | Phenotype | yes | | PhenotypeDetails | Fails to grow under N2-fixing conditions; but grows normally with nitrate or ammonium | | Comment | In the same gene cluster as prpA | | Medline | 9573144 |
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| all7120 | Genes and Mutants | | Genes and Mutants | posted by chunxia dong <dongcx at 263.net> at 2004-06-30 |
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| GeneName | nblA |
|
| Genes and Mutants | | Genes and Mutants | posted by chunxia dong <dongcx at 263.net> at 2004-06-30 |
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| GeneName | nblA |
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| Genes and Mutants | | Genes and Mutants | posted by chunxia dong <dongcx at 263.net> at 2004-06-30 |
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| GeneName | nblA |
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| alr1602 | Genes and Mutants | | Genes and Mutants | posted by Takakazu Kaneko <kaneko at kazusa.or.jp> at 2006-10-31 |
|---|
| Comment | alr1602 was initially annotated as glucose-6-phosphate dehydrogenase(devB), because we referred to annotation from GenBank Accession: U14553. We made reannotaion of alr1602 based on the similarity, but we don't have any experimental evidence supporting the function. |
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| alr4164 | Genes and Mutants | | Genes and Mutants | posted by Enrique Flores <eflores at ibvf.csic.es> at 2008-02-28 |
|---|
| MutantName | CSR17 | | GeneName | natF | | ProductName | Periplasmic substrate-binding protein of the ABC-type transporter N-II | | Function | Transport of acidic and polar neutral amino acids. | | Phenotype | yes | | PhenotypeDetails | Impaired amino acid transport and impaired diazotrophic growth | | DrugMarker | Nm/Km | | Medline | 18208492 |
|
| alr1834 | Genes and Mutants | | Genes and Mutants | posted by Enrique Flores <eflores at ibvf.csic.es> at 2008-02-28 |
|---|
| MutantName | CSS6 | | GeneName | natB | | ProductName | Periplasmic substrate-binding protein of the ABC-type transporter N-I | | Function | Transport of proline and hydrophobic amino acids | | Phenotype | yes | | PhenotypeDetails | Impaired amino acid transport and impaired diazotrophic growth. | | DrugMarker | Sm/Sp | | Medline | 18208492 |
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| alr3727 | Genes and Mutants | | Genes and Mutants | posted by Cosmin Ionel Sicora <Cossic at utu.fi> at 2008-01-02 |
|---|
| GeneName | psbAII | | ProductName | D1:2 subunit of PSII | | Function | D1:2 isoform replaces D1:1 under stress conditions. | | Medline | 16388778 |
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| all5341 | Genes and Mutants | | Genes and Mutants | posted by Koichiro Awai <awai at molbiol.saitama-u.ac.jp> at 2007-12-07 |
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| MutantName | hglT | | GeneName | HglT | | ProductName | Heterocyst specific glycolipid synthase | | Function | Glycosyltransferase catalyzes glucose transfer to hexacosane-1,3,25-triol. | | Phenotype | yes | | PhenotypeDetails | Sensitive to nitrogen deprivation. | | DrugMarker | erythromycin | | Medline | 17233720 |
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| all4813 | Genes and Mutants | |
| alr2502 | Genes and Mutants | | Genes and Mutants | posted by Cheng-Cai Zhang <cczhang at ibsm.cnrs-mrs.fr> at 2007-05-22 |
|---|
| MutantName | Mp22 | | GeneName | pkn22 | | ProductName | Pkn22 | | Function | A putative Ser/Thr kinase involved in iron homeostasis. Cotranscribed with PrxQ-A | | PhenotypeDetails | Has severe pheotypes under oxidative stress | | Medline | 14550569 |
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| all1731 | Genes and Mutants | | Genes and Mutants | posted by Cheng-Cai Zhang <cczhang at ibsm.cnrs-mrs.fr> at 2007-05-22 |
|---|
| MutantName | S20 | | GeneName | all1731 | | ProductName | PrpJ | | Function | A protein Ser/Thr and Tyr phosphatase. Required for heterocyst glycolipid synthesis | | PhenotypeDetails | In the presence of a combined nitrogen source, it grows well. Under diazotrophic conditions, the mutant (S20) did not grow, lacked only one of the two heterocyst glycolipids, and fragmented extensively at the junctions between developing cells and vegetative cells. | | Medline | 17371502 |
|
| Genes and Mutants | | Genes and Mutants | posted by Cheng-Cai Zhang <cczhang at ibsm.cnrs-mrs.fr> at 2007-06-01 |
|---|
| GeneName | prpJ | | ProductName | PrpJ |
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| alr3189 | Genes and Mutants | | Genes and Mutants | posted by Shinichi Takaichi <takaichi at nms.ac.jp> at 2007-05-18 |
|---|
| MutantName | delta-crtW | | GeneName | crtW | | ProductName | beta-carotene ketolase | | Function | Ketolation of myxol-fucoside to ketomyxol fucoside | | PhenotypeDetails | Carotenoid composition is different (Ketomyxol fucoside is absent) | | DrugDirection | Rv | | DrugMarker | Nm | | Medline | 16242129 |
|
| all1076 | Genes and Mutants | | Genes and Mutants | posted by Marty Lee <martylee54 at nsm.com> at 2003-10-05 |
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| MutantName | AMC1050 | | GeneName | plmA | | ProductName | PlmA | | Function | Transcriptional regulator of unknown target. | | Phenotype | yes | | PhenotypeDetails | Knockout mutations in plmA decrease the copy number of endogenous plasmids Zeta and Delta. The mutation also decreases the copy number of exogenous plasmids that are based on the pDU1 replicon. The phenotype was checked by introducing a patS-overexpression vector (pAM1651, making mutant strain AMC1051) and checking that heterocysts still developed. | | DrugMarker | Sp/Sm | | AdditionalInformation | The email address given above is slightly altered to avoid spam 'bots. The correct address should be "msn" rather than "nsm" | | Comment | Member of the GntR family of transcriptional regulators, clustering with a number of similar genes that are all found in cyanobacteria. | | Medline | 12867439 |
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| alr4165 | Genes and Mutants | | Genes and Mutants | posted by Enrique Flores <eflores at ibvf.csic.es> at 2008-02-28 |
|---|
| GeneName | natG | | ProductName | Transmembrane protein of the ABC-type transporter N-II | | Function | Transport of acidic and polar neutral amino acids | | Medline | 18208492 |
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| all1047 | Genes and Mutants | | Genes and Mutants | posted by Enrique Flores <eflores at ibvf.csic.es> at 2008-02-28 |
|---|
| MutantName | CSX62 | | GeneName | natC | | ProductName | Transmembrane protein of the ABC-type transporter N-I | | Function | Transport of proline and hydrophobic amino acids | | Phenotype | yes | | PhenotypeDetails | Impaired amino acid transport and impaired diazotrophic growth. | | DrugMarker | Sm/Sp | | AdditionalInformation | Medline ID: 18208492 | | Medline | 16135226 |
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| alr4866 | Genes and Mutants | | Genes and Mutants | posted by Cosmin Ionel Sicora <cossic at utu.fi> at 2008-01-02 |
|---|
| GeneName | psbAI | | ProductName | D1:1 Subunit of PSII | | Function | Encodes a constitutively expressed D1 isoform. | | Comment | Expressed at high level under normal growth conditions is down regulated under stress. | | Medline | 16388778 |
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| alr2503 | Genes and Mutants | | Genes and Mutants | posted by Amel Latifi <latifi at ibsm.cnrs-mrs.fr> at 2007-05-22 |
|---|
| MutantName | Mp22 | | GeneName | alr2503 | | ProductName | PrxQ-A | | Function | A peroxiredoxin. Involved in oxidative stress response | | PhenotypeDetails | The mutant disrupts a gene pkn22 in the upstream region of alr2503. There is a polar effect on the expression of alr2503.Does not grow under oxidative stress conditions | | Medline | 17210455 |
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| alr4166 | Genes and Mutants | | Genes and Mutants | posted by Enrique Flores <eflores at ibvf.csic.es> at 2008-02-28 |
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| MutantName | CSR8a | | GeneName | natH | | ProductName | Transmembrane protein of the ABC-type transporter N-II | | Function | Transport of acidic and polar neutral amino acids | | Phenotype | yes | | PhenotypeDetails | Impaired amino acid transport and impaired diazotrophic growth. | | DrugMarker | Sm/Sp | | Medline | 18208492 |
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| all1046 | Genes and Mutants | | Genes and Mutants | posted by Enrique Flores <eflores at ibvf.csic.es> at 2008-02-28 |
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| MutantName | CSX60 | | GeneName | natA | | ProductName | ATPase subunit of the ABC-type transporter N-I | | Function | Transport of proline and hydrophobic amino acids | | Phenotype | yes | | PhenotypeDetails | Impaired amino acid transport and impaired diazotrophic growth; release from the cells of hydrophobic amino acids, which accumulate in the extracellular medium. | | DrugMarker | Sm/Sp | | Medline | 18208492 |
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| alr2338 | Genes and Mutants | | Genes and Mutants | posted by Enrique Flores <eflores at ibvf.csic.es> at 2008-02-28 |
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| MutantName | SR2787a | | GeneName | sepJ | | ProductName | SepJ | | Function | Septum-localized protein required for filament integrity and heterocyst development. | | Phenotype | yes | | PhenotypeDetails | Filament fragmentation; Het-, Fox-, Fix- | | DrugMarker | erythromycin resistance | | Comment | The SepJ protein has two well differentiated parts: the N-terminal half is preditected to be extracytoplasmic and contains coiled-coil and extensin-like domains; the C-terminal half is homologous to proteins of the DME family of exporters | | Medline | 17369306 |
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| alr4592 | Genes and Mutants | | Genes and Mutants | posted by Cosmin Ionel Sicora <cossic at utu.fi> at 2008-01-02 |
|---|
| GeneName | psbAIII | | ProductName | D1:2 subunit of PSII | | Function | D1:2 replaces D1:1 isoform under stress conditions. | | Medline | 16388778 |
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| all1625 | Genes and Mutants | | Genes and Mutants | posted by Cheng-Cai Zhang <cczhang at ibsm.cnrs-mrs.fr> at 2007-05-22 |
|---|
| GeneName | pkn44 | | ProductName | Pkn44 | | Function | A member of the HstK family, with both a Ser/Thr kinase domain and a His kinase domain. Involved in heterocyst development | | Phenotype | yes | | PhenotypeDetails | No phenotype when inactivated alone. However, when inactivated together with pkn30, the double mutant lacks one heterocyst-specific glycolipid, and doesn't grow under diazotrophic conditions. | | Medline | 17513480 |
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| all3744 | Genes and Mutants | | Genes and Mutants | posted by Shinichi Takaichi <takaichi at nms.ac.jp> at 2007-05-17 |
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| MutantName | delta-crtO | | GeneName | crtO | | ProductName | beta-carotene ketolase | | Function | Synthesis of echinenone from beta-carotene | | Phenotype | yes | | PhenotypeDetails | Carotenoid composition is different (Echinenone is absent). | | DrugDirection | Fw | | DrugMarker | Nm | | Medline | 16242129 |
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| alr4674 | Genes and Mutants | | Genes and Mutants | posted by Iris Maldener <iris.maldener at biologie.uni-regensburg.de> at 2005-03-30 |
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| MutantName | DRpMA54 | | GeneName | devT | | ProductName | Ser/Thr protein phosphatase, PPP family | | Function | Ser/Thr protein phosphatase catalyzes dephosphorylation of proteins on serine and threonine, respectively | | Phenotype | yes | | PhenotypeDetails | no aerobic nitrogen fixation, non-functional heterocysts with normal morphology | | DrugDirection | Rv | | DrugMarker | Nm | | Comment | DevT shows manganese dependent phosphatase activity in vitro. |
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| all7280 | Genes and Mutants | | Genes and Mutants | posted by jeff Elhai <ElhaiJ at VCU.Edu> at 2008-03-03 |
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| GeneName | dmtE | | ProductName | solitary Type II DNA methyl-transferase | | Function | N6-methylation of adenine within GATC | | Comment | Matveyev, AV, Young KT, Meng A, Elhai J (2001). DNA methyltransferases of the cyanobacterium Anabaena PCC 7120. Nucl Acids Res 29:1491-1506.Formerly known as dmnA. |
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| alr4167 | Genes and Mutants | | Genes and Mutants | posted by Enrique Flores <eflores at ibvf.csic.es> at 2008-02-28 |
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| MutantName | CSR10 | | GeneName | bgtA | | ProductName | ATPase subunit of the ABC-type transporters N-II and Bgt | | Function | Transport of basic, acidic, and polar neutral amino acids. | | Phenotype | yes | | PhenotypeDetails | Impaired amino acid transport and impaired diazotrophic growth | | DrugMarker | Sm/Sp | | Comment | BgtA contributes to two different ABC-type transporters: N-II (acidic and polar neutral amino acids) and Bgt (basic amino acids) | | Medline | 18208492 |
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| all3572 | Genes and Mutants | | Genes and Mutants | posted by Cosmin Ionel Sicora <cossic at utu.fi> at 2008-01-02 |
|---|
| GeneName | psbAIV | | ProductName | D1:2 subunit of PSII | | Function | D1:2 replaces D1:1 under stress conditions. | | Medline | 16388778 |
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| all3691 | Genes and Mutants | | Genes and Mutants | posted by Cheng-Cai Zhang <cczhang at ibsm.cnrs-mrs.fr> at 2007-05-22 |
|---|
| GeneName | pkn30 | | ProductName | Pkn30 | | Function | A member of the HstK family, with both a Ser/Thr kinase domain and a His kinase domain. Involved in heterocyst development | | Phenotype | yes | | PhenotypeDetails | No phenotype when inactivated alone. However, when inactivated together with pkn44, the double mutant lacks one heterocyst-specific glycolipid, and doesn't grow under diazotrophic conditions. | | Medline | 17513480 |
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| alr4366 | Genes and Mutants | | Genes and Mutants | posted by Cheng-Cai Zhang <cczhang at ibsm.cnrs-mrs.fr> at 2007-05-22 |
|---|
| GeneName | pknA | | ProductName | PknA | | Function | A putative Ser/Thr kinase, maybe involved in heterocyst development | | Phenotype | yes | | PhenotypeDetails | weak phenotypes under N-limiting conditions | | Medline | 7505448 |
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| all1950 | Genes and Mutants | | Genes and Mutants | posted by Enrique Flores <eflores at ibvf.csic.es> at 2008-02-28 |
|---|
| MutantName | CSAV5 | | GeneName | urtB | | ProductName | Transmembrane protein of the ABC-type transporter Urt | | Function | Transport of urea | | Phenotype | yes | | PhenotypeDetails | Impaired urea transport | | DrugMarker | Sm/Sp | | Medline | 11929526 |
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| all1947 | Genes and Mutants | | Genes and Mutants | posted by Enrique Flores <eflores at ibvf.csic.es> at 2008-02-28 |
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| MutantName | CSAV2 | | GeneName | urtE | | ProductName | ATPase subunit of the ABC-type transporter Urt | | Function | Transport of urea | | Phenotype | yes | | PhenotypeDetails | Impaired urea transport | | DrugMarker | Nm/Km | | Medline | 11929526 |
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| alr3742 | Genes and Mutants | | Genes and Mutants | posted by Cosmin Ionel Sicora <cossic at utu.fi> at 2008-01-02 |
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| GeneName | psbA0 | | ProductName | D1 subunit of PSII | | Function | Part of the PSII complex. | | Comment | The D1 form encoded is divergent expressed at trace levels and has unknown function | | Medline | 16388778 |
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| all1948 | Genes and Mutants | |
| alr4368 | Genes and Mutants | | Genes and Mutants | posted by Cheng-Cai Zhang <cczhang at ibsm.cnrs-mrs.fr> at 2007-05-22 |
|---|
| GeneName | pknD | | ProductName | PknD | | Function | A putative Ser/Thr kinase, maybe involved in nitrogen metabolism or trafficking | | Phenotype | yes | | PhenotypeDetails | Fix N2 normally, but grows less well than wild type under N2-fixing conditions. Grows normally with ammonium in the medium | | Medline | 9613569 |
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| alr0975 | Genes and Mutants | | Genes and Mutants | posted by Kazumasa Hirata <hirata at phs.osaka-u.ac.jp> at 2004-02-06 |
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| GeneName | alr0975 | | ProductName | primitive phytochelatin synthase | | Function | Primitive phytochelatin synthase catalyzes the formation of gamma-glutamylcysteine with the cleavage of glycine from glutathione. | | AdditionalInformation | Phone number:+81-06-6879-8239. Fax number:+81-06-6879-8239 | | Comment | This protein also synthesizes low level of phytochelatin2 by transfering of the gamma-glutamylcysteine unit to an acceptor glutathione molecule. |
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| asl1922 | Genes and Mutants | | Genes and Mutants | posted by Daniel Picot & Ajlani <picot at ibpc.fr> at 2003-11-23 |
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| GeneName | petL | | ProductName | PetL | | Function | small subunit of cytochrome b6f complex | | Comment | homologous to chloroplast PetL |
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| all1949 | Genes and Mutants | | Genes and Mutants | posted by Enrique Flores <eflores at ibvf.csic.es> at 2008-02-28 |
|---|
| GeneName | urtC | | ProductName | Transmembrane protein of the ABC-type transporter Urt | | Function | Transport of urea | | Medline | 11929526 |
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| all2912 | Genes and Mutants | | Genes and Mutants | posted by Enrique Flores <eflores at ibvf.csic.es> at 2008-02-28 |
|---|
| MutantName | CSR5 | | GeneName | natE | | ProductName | ATPase subunit of the ABC-type transporter N-I | | Function | Transport of proline and hydrophobic amino acids | | Phenotype | yes | | PhenotypeDetails | Impaired amino acid transport and impaired diazotrophic growth. | | DrugMarker | Nm/Km | | AdditionalInformation | Medline ID: 18208492 | | Medline | 16135226 |
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| alr2258 | Genes and Mutants | | Genes and Mutants | posted by Cheng-Cai Zhang <cczhang at ibsm.cnrs-mrs.fr> at 2007-05-22 |
|---|
| GeneName | hstK | | ProductName | HstK | | Function | A protein with both a Ser/Thr kinase domain and a His kinase domain. Member of a family of 13 genes in Anabaena. Some of them are involved in iron homeostasis or heterocyst development | | Phenotype | no | | AdditionalInformation | See also publications in pubmed 16788191, 16415589, and 12480098 | | Medline | 11736654 |
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| alr0709 | Genes and Mutants | | Genes and Mutants | posted by Cheng-Cai Zhang <cczhang at ibsm.cnrs-mrs.fr> at 2007-05-22 |
|---|
| MutantName | deltapkn41 | | GeneName | alr0709 | | ProductName | Pkn41 | | Function | Involved in iron homeostasis and nitrogen control | | PhenotypeDetails | Grows less well in the presence of an iron chelator. When inactivated together with pkn42, the corresponding mutant shows a severe phenotype when both iron and combined nitrogen are limiting | | Medline | 16788191 |
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| all1951 | Genes and Mutants | | Genes and Mutants | posted by Enrique Flores <eflores at ibvf.csic.es> at 2008-02-28 |
|---|
| MutantName | CSAV4 | | GeneName | urtA | | ProductName | Periplasmic substrate-binding protein of the ABC-type transporter Urt | | Function | Urea transport | | Phenotype | yes | | PhenotypeDetails | Impaired urea transport | | DrugMarker | Sm/Sp | | Medline | 11929526 |
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| alr2259 | Genes and Mutants | | Genes and Mutants | posted by Cheng-Cai Zhang <cczhang at ibsm.cnrs-mrs.fr> at 2007-05-22 |
|---|
| GeneName | pknB | | ProductName | PknB | | Function | A putative Ser/Thr kinase with unkown function. In the same gene cluster as hstK. | | Phenotype | no | | Medline | 11736654 |
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| alr4516 | Genes and Mutants | | Genes and Mutants | posted by Cheng-Cai Zhang <cczhang at ibsm.cnrs-mrs.fr> at 2007-05-22 |
|---|
| MutantName | deltaprpS | | GeneName | prpS | | ProductName | PrpS | | Function | A PP2C-type protein phosphatase involved in nitrogen metabolism | | PhenotypeDetails | Shows abberant pattern of PII phosphorylation. Accumulates cyanophycin | | Medline | 15474048 |
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